The small West African nation of Guinea-Bissau is confronting an unprecedented public health challenge as it battles its first-ever mpox outbreak. Since the epidemic was declared on 4 July the country has reported seven confirmed cases and 46 suspected cases with a alarming trend: more than half of these cases have been among children.
The situation has raised serious concerns among health authorities and international organizations, who warn that the virus is likely spreading undetected due to the country’s fragile health surveillance systems. This outbreak comes at a time when Guinea-Bissau is already struggling with infrastructure challenges and the aftermath of political instability.
Children bear the brunt of the outbreak
Among the most worrying aspects of this outbreak is the high number of pediatric cases. 16 children under the age of four have been affected, highlighting the particular vulnerability of this age group. Unicef has expressed grave concerns about the potential for further spread among children, emphasizing the need for enhanced surveillance and community awareness.
Sandra Martins Unicef’s deputy representative in Guinea-Bissau, underscored the gravity of the situation: “This is the first time mpox cases have been reported in Guinea-Bissau, making even a small outbreak a major public health event.” The organization has been working closely with local authorities to implement public awareness campaigns and strengthen health systems to better respond to the crisis.
Health system challenges and cross-border risks
The outbreak has exposed significant gaps in Guinea-Bissau’s health infrastructure. Many public health laboratories in the region lack adequate equipment to handle epidemics effectively. However, they do possess institutional knowledge from managing other health crises, which could prove valuable in this situation.
Health workers have noted that the Clade variants of mpox circulating in Guinea-Bissau are consistent with those found in neighboring countries. This raises concerns about the potential for cross-border transmission and the need for regional cooperation to contain the outbreak. The vast majority of confirmed cases are concentrated in the Bissau autonomous sector with one case reported in the nearby Biombo area.
Dr. Magda Robalo a former health minister and co-founder of the Institute for Global Health and Development emphasized the importance of prioritizing increased surveillance and reinforcing frontline capacity. She noted that while the numbers may seem small, the intermittent appearance of new cases over several weeks indicates ongoing transmission.
Community response and public awareness
In response to the outbreak, community health workers have launched door-to-door public awareness campaigns using megaphones and translated leaflets. These efforts, supported by the health ministry and international agencies, are seen as vital for building public trust in the public health sector.
The outbreak comes as the country prepares for the reopening of primary schools in September, adding urgency to the situation. The public awareness campaigns aim to educate communities about the risks of mpox and the importance of preventive measures to protect children and vulnerable populations.
The outbreak also follows the suspension of a controversial US-funded trial on hepatitis B vaccinations for newborns earlier this year. The decision to suspend the trial highlighted sensitivities around emergency health interventions and the need for ethical considerations in public health initiatives.
As Guinea-Bissau grapples with this unprecedented health challenge, the international community continues to monitor the situation closely. The outbreak serves as a stark reminder of the importance of robust health systems and the need for ongoing vigilance in the face of emerging public health threats.



