In the realm of medical history, the invention of modern anesthetics in 1846 is often celebrated as a groundbreaking achievement. However, recent research has unveiled that ancient Chinese surgeons were already employing sophisticated techniques to alleviate surgical pain centuries earlier. This discovery not only reshapes our understanding of early medical practices but also highlights the ingenuity of ancient physicians.
The findings center on a set of iron surgical scissors and tweezers belonging to Xia Quana renowned traditional Chinese medicine surgeon from the early Ming Dynasty (1368–1644). These instruments, recovered from Xia Quan’s tomb in Jiangyin County, Chinahave provided rare physical evidence of ancient anesthetic practices. Advanced analytical techniques recently detected traces of aconitinea potent toxin found in plants of the Aconitum genus, commonly known as wolfsbane or monkshood.
Clues Hidden on Ancient Surgical Tools
Historical texts have long described the use of herbal anesthetics in China, but direct physical evidence has been scarce. The newly identified chemical traces on Xia Quan’s surgical tools strongly support the idea that physicians prepared specialized plant-based mixtures for surgical procedures. Researchers believe that surgeons applied processed aconitine directly to a patient’s skin before surgery to numb the treatment area and reduce pain.
By carefully handling and refining such a dangerous substance, these physicians demonstrated a sophisticated understanding of medicinal plants and human physiology. This practice, known as Caowu Saninvolved processing the toxic plant through methods such as soaking it in vinegar, black soy sauce, or even urine to reduce its harmful effects. This meticulous preparation allowed for the creation of a local anesthetic that could be applied topically to minimize pain during surgical procedures.
The Significance of the Discovery
The discovery challenges the notion that effective anesthesia emerged only in the modern era. Instead, it highlights the ingenuity of Ming Dynasty physicians, who developed practical approaches to pain management long before doctors introduced ether and other modern anesthetics. This finding not only sheds light on ancient Chinese medical practices but also reveals how early physicians combined observation, experimentation, and herbal knowledge to make surgical procedures safer and more tolerable for their patients.
Professor Congcang Zhao of Northwest University in China led the research team that made this remarkable discovery. Using advanced techniques such as Microscopía de Dispersión Raman Estimulada (SRS)they were able to identify the chemical composition of the residues trapped in the metal’s oxide without damaging the archaeological pieces. This non-destructive method provided crucial insights into the ancient medical practices of the Ming Dynasty.
The findings were published on June 13, 2026and have since sparked widespread interest among historians, archaeologists, and medical professionals. The discovery not only provides a deeper understanding of ancient Chinese medical practices but also offers a glimpse into the advanced knowledge and techniques employed by physicians of that era.
As we continue to explore the rich history of medicine, this discovery serves as a reminder of the ingenuity and innovation of ancient civilizations. It challenges our preconceived notions of medical progress and highlights the enduring legacy of traditional medical practices.



